Venous thrombosis represents a spectrum of diseases that includes both deep venous thrombosis (DVT) and pulmonary embolism (1). Often, DVT is not suspected clinically leading to significant diagnostic delays. Venous thrombosis results in considerable, but potentially preventable, morbidity and mortality among hospitalized patients. Most of the hospitalized patients have a high risk of DVT, and hospitalization for acute medical-illness is known to be associated with about eight-fold increased risk of DVT (2). Because of the high rate of missed diagnosis, the true incidence of DVT is unknown. There is a lack of adequate studies on the incidence of DVT. Only a few studies exist published literature most of which were done on surgical patients. There are little published data available on the risk of DVT among hospitalized medically-ill patients. Hence, we sought to study the profile of risk factors and the incidence of DVT among medically-ill patients treated at a tertiary care hospital in northern India.