Associations Between Asthma and Bronchial Hyper-Responsiveness with Allergy and Atopy Phenotypes in Urban Black South African Teenagers (Original Articles) (Report)

Associations Between Asthma and Bronchial Hyper-Responsiveness with Allergy and Atopy Phenotypes in Urban Black South African Teenagers (Original Articles) (Report)

Studies in South Africa in the 1970s reported very low rates of asthma in indigenous blacks, (1) especially in rural settings. (2) The subjects also demonstrated low rates of allergen sensitisation. Later studies showed increasing prevalence rates of asthma in urban and rural black communities (3,4) and narrowing of the urban-rural gradient. (5) An increased allergen sensitisation rate was also noted in rural blacks, (6) with different patterns of sensitisation in those with or without bronchial hyper-responsiveness (BHR). (5) There are few data on BHR rates in urban black children, associations between asthma and BHR, and the relationship between BHR, allergen sensitisation and other atopic diseases. We aimed to determine asthma and allergy phenotypes in unselected urban black teenagers and to associate BHR with asthma, other atopic diseases and allergen sensitisation.

Associations Between Asthma and Bronchial Hyper-Responsiveness with Allergy and Atopy Phenotypes in Urban Black South African Teenagers (Original Articles) (Report)



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