Clinical Significance of Airways Colonization with Ureaplasma Urealyticum in Premature (34 Wk) Neonates.
Background & objectives: Ureaplasma urealyticum has been implicated in various neonatal morbidities in preterm infants. Its association with chronic lung disease (CLD) remains controversial. The aim of this prospective study was to investigate colonization of U. urealyticum in preterm infants (with gestational age 34 wk) and to evaluate the relationship between U. urealyticum colonization and neonatal morbidity including CLD. Methods: U. urealyticum was cultured from nasopharyngeal or endotracheal aspirates collected within 24 h of birth from infant [greater than or equal to] 34 wk gestation weighing 1800 g admitted to a Neonatal Intensive Care Unit of a tertiary care hospital in north India, and PCR was performed on the DNA extracted from these samples.