Cutaneous Malakoplakia (Resident Short Reviews) (Report)

Cutaneous Malakoplakia (Resident Short Reviews) (Report)

Malakoplakia is an acquired granulomatous disorder that was initially described in the bladder by Michaelis and Gutmann (1) in 1902 and later by von Hansemann (2) in 1903 who named the lesion malakoplakia meaning “soft plaque.” Since its initial description, more than 400 cases have been described in numerous anatomic locations including the bladder, kidney, prostate, testis, pancreas, oropharynx, retroperitoneum, thyroid gland, lymph nodes, lung, bone/joint, and brain. (3-6) The majority of the lesions occur in the genitourinary tract, accounting for 60% to 70% of the cases (6,7) with bladder involvement in up to 40% of the cases. (5) Cutaneous involvement by malakoplakia was first reported in 1969 in a 40-year-old woman with an inguinal ulcer that was continuous with a broad ligament mass. (8) Leclerc and Bernier (9) reported the first case of primary cutaneous malakoplakia in 1972 in a 64-year-old man with rheumatoid arthritis and a perianal lesion. Since that time, fewer than 50 cases of primary cutaneous malakoplakia have been reported in the literature (Table). (3,7-41) CLINICAL FEATURES

Cutaneous Malakoplakia (Resident Short Reviews) (Report)

Cutaneous Malakoplakia (Resident Short Reviews) (Report) | | 4.5