Dose Adjustment–an Important Issue in Critical Care (Clinical Knowledge)

Dose Adjustment--an Important Issue in Critical Care (Clinical Knowledge)

ABSTRACT: There is at times marked variability in drug responsiveness especially in critically ill patients admitted in the Intensive care units. In order to obtain therapeutic effectiveness with in pharmacokinetic parameters related to therapeutic dose, it is always desirable to monitor and to maintain drug dose adjustment in such a way especially in presence of organ failure like renal failure, hepatic failure or any other clinical situation necessitating Therapeutic Drug Monitoring (TDM) so that one can use safe and effective drug therapy with least toxicity due to inaccurate and invalid drug doses. KEY WORDS: Drug, Dose adjustment, Patient’s care, Adverse drug reaction.

Dose Adjustment--an Important Issue in Critical Care (Clinical Knowledge)

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