Estimating the Burden of Disease Attributable to Vitamin A Deficiency in South Africa in 2000 (Original Articles)
Objectives. To estimate the burden of disease attributable to vitamin A deficiency in children aged 0-4 years and pregnant women aged 15-49 years in South Africa in 2000. Design. The framework adopted for the most recent World Health Organization comparative risk assessment (CRA) methodology was followed. Population-attributable fractions were calculated from South African Vitamin A Consultative Group (SAVACG) survey data on the prevalence of vitamin A deficiency in children and the relative risks of associated health problems, applied to revised burden of disease estimates for South Africa in the year 2000. Small community studies were used to derive the prevalence in pregnant women. Monte Carlo simulation-modelling techniques were used for the uncertainty analysis.