High Incidence of Zidovudine Induced Anaemia in HIV Infected Patients in Eastern India (Report)

High Incidence of Zidovudine Induced Anaemia in HIV Infected Patients in Eastern India (Report)

Availability of free antiretroviral drugs to HIV infected individuals in India and other countries has provided a new lease of life to these patients. However, resource constraints limit the national programme to use nucleoside reverse transcriptase inhibitors (NRTIs) like zidovudine (AZT) or stavudine (d4T) with lamivudine (3TC) and non nucleoside reverse transcriptase inhibitors (NNRTI) like nevirapine and efavirenz for highly active anti-retroviral therapy (HAART). Due to mitochondrial toxicity with long term use of stavudine (d4T), it is no longer recommended (1) and zidovudine (AZT) is the preferred NRTI in the National AIDS Control Organization (NACO) sponsored ART centres in India (2). This drug, though highly effective, is also associated with potentially life threatening and morbid side effects mainly myelotoxicity, manifesting clinically as anaemia (3). The prevalence of zidovudine induced anaemia vary widely (5.42-9.62%), in studies from different parts of the world (4,5). There are very few studies on prevalence of zidovudine induced anaemia in India. Hence this study was undertaken with the aim to find out the prevalence of zidovudine induced anaemia in patients initiated on zidovudine containing regimen and to look at correlates, if any, for precipitating AZT induced anaemia in a tertiary care centre in eastern India. Material & Methods

High Incidence of Zidovudine Induced Anaemia in HIV Infected Patients in Eastern India (Report)



Here is Download Link

Issues In Discovery Experimental And Laboratory Medicine 2011 Edition


Issues In Discovery Experimental And Laboratory Medicine 2011 Edition Read Online Download

Author by :
Languange Used : en
Release Date : 2012-01-09
Publisher by : ScholarlyEditions






Hiv Aids Treatment And Care


Hiv Aids Treatment And Care Read Online Download

Author by : Irina Eramova
Languange Used : en
Release Date : 2007
Publisher by :






Consolidated Guidelines On The Use Of Antiretroviral Drugs For Treating And Preventing Hiv Infection


Consolidated Guidelines On The Use Of Antiretroviral Drugs For Treating And Preventing Hiv Infection Read Online Download

Author by : World Health Organization
Languange Used : en
Release Date : 2016
Publisher by :






Economics Of Aids And Access To Hiv Aids Care In Developing Countries


Economics Of Aids And Access To Hiv Aids Care In Developing Countries Read Online Download

Author by : Jean-Paul Moatti
Languange Used : en
Release Date : 2003
Publisher by :






Cumulated Index Medicus


Cumulated Index Medicus Read Online Download

Author by :
Languange Used : en
Release Date : 2000
Publisher by :






Risk Factors For Adverse Drug Reactions Epidemiological Approaches


Risk Factors For Adverse Drug Reactions Epidemiological Approaches Read Online Download

Author by : Weber
Languange Used : en
Release Date : 2012-03-08
Publisher by : Birkhäuser






Guidelines For The Treatment Of Malaria


Guidelines For The Treatment Of Malaria Read Online Download

Author by : World Health Organization
Languange Used : en
Release Date : 2010
Publisher by : World Health Organization






Leave a Reply

Your email address will not be published. Required fields are marked *