The seventh edition has been revised and updated to address our understanding of medical management for diseases caused by threat pathogens. Medical professionals learn about effective available medical countermeasures against many of the bacteria, viruses, and toxins that might be used as biological weapons against military forces or civilian communities.The purpose of this handbook is to serve as a concise, pocket-sixed manual that can be pulled off the shelf (or from a pocket) in a crisis to guide medical personnel in the prophylaxis and management of biological casualties. It is designed as a quick reference and overview, and is not intended as a definitive text. A greater in-depth discussion of the agents covered here may be found in the Army Surgeon General’s Borden Institute Textbook of Military Medicine, “Medical Aspects of Biological Warfare” (2007) and in relevant infectious disease, tropical medicine, and disaster management textbooks.The Medical Management of Biological Casualties Handbook, which has been known as the “Blue Book” has been enormously successful. Since the first edition in 1993, the awareness of biological weapons in the U.S. has increased dramatically. Over 190,000 copies have been distributed to military and civilian healthcare providers around the world.