Modification of Medical Device Surface to Attain Anti-Infection.

Modification of Medical Device Surface to Attain Anti-Infection.

Extensive use of antibiotics to treat device-associated infections has contributed to the acceleration of the appearance of antibiotic-resistant bacteria by spreading through contaminated hospital environments to patients (1,2). Comprehensive research has had limited success in the reduction of device-associated infections, and usually the only therapy to treat the infections is removal of the infected devices from patients. Recent strategies to minimize the risks of device-associated infections have focused on the following areas: good clinical practices, prudent selection of biomaterials used for device construction, and modification of device surfaces by increasing surface biocompatibility and decreasing bacterial adherence. The elements of bacterial adhesion on indwelling device surfaces that may directly relate to infections and will study surface treatment technologies in reducing the incidence of indwelling medical device-related infections. In the following text these topics will be discussed from several aspects. Introduction

Modification of Medical Device Surface to Attain Anti-Infection.



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