Multi-Center Surveillance for Pneumonia & Meningitis Among Children (2 Yr) for Hib Vaccine Probe Trial Preparation in India (Report)

Multi-Center Surveillance for Pneumonia & Meningitis Among Children (2 Yr) for Hib Vaccine Probe Trial Preparation in India (Report)

Introduction Haemophilus influenzae has long been recognised as a cause of serious infections (i.e., pneumonia and meningitis) and mortality in children less than 5 yr old. Prior to the introduction of H. influenzae type b (Hib) immunization, the incidence of invasive Hib infection was 20-50/100,000 children 5 yr of age in industrialized countries and higher in developing regions (1-5). Within two years of the introduction of routine Hib vaccination of infants in the UK, the risk of serious Hib infection fell from 1:600 to 1:30,000 among children 5 yr of age (1,6,7). Hib meningitis has been virtually eliminated in a number of developing countries where Hib vaccine has been introduced into the routine immunisation programmes (8,9).

Multi-Center Surveillance for Pneumonia & Meningitis Among Children (2 Yr) for Hib Vaccine Probe Trial Preparation in India (Report)

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