Palonosetron (Aloxi): A Second-Generation 5-H[T.Sub.3] Receptor Antagonist for Chemotherapy-Induced Nausea and Vomiting (Pharmacology Notes) (Drug Overview)

Palonosetron (Aloxi): A Second-Generation 5-H[T.Sub.3] Receptor Antagonist for Chemotherapy-Induced Nausea and Vomiting (Pharmacology Notes) (Drug Overview)

In July 2003, the Food and Drug Administration approved palonosetron hydrochloride injection for the treatment of chemotherapy-induced nausea and vomiting (CINV). The newest agent in the class of 5-H[T.sub.3] receptor antagonists (5-H[T.sub.3]RAs), palonosetron differs from other agents in its class by its higher receptor-binding affinity and longer half-life. These pharmacological properties have resulted in improved antiemetic activity in clinical trials, particularly in the treatment of delayed CINV following moderate emetogenic chemotherapy. Based on the results of these clinical studies, palonosetron is the only 5-H[T.sub.3]RA approved for delayed CINV. Palonosetron is given as a single 0.25-mg intravenous dose 30 minutes before the initial dose of chemotherapy. Headache and constipation were the most common adverse events reported with palonosetron therapy. **********

Palonosetron (Aloxi): A Second-Generation 5-H[T.Sub.3] Receptor Antagonist for Chemotherapy-Induced Nausea and Vomiting (Pharmacology Notes) (Drug Overview)



Here is Download Link

Management Of Chemotherapy Induced Nausea And Vomiting


Management Of Chemotherapy Induced Nausea And Vomiting Read Online Download

Author by : Rudolph M. Navari
Languange Used : en
Release Date : 2016-01-25
Publisher by : Springer






Navelbine Vinorelbine


Navelbine Vinorelbine Read Online Download

Author by : Philippe Solal-Celigny
Languange Used : en
Release Date : 1990
Publisher by : John Libbey Eurotext






Pocket Guide To Gastrointestinai Drugs


Pocket Guide To Gastrointestinai Drugs Read Online Download

Author by : M. Michael Wolfe
Languange Used : en
Release Date : 2014-01-02
Publisher by : John Wiley & Sons






Short Answer Questions In Anaesthesia


Short Answer Questions In Anaesthesia Read Online Download

Author by : Simon Bricker
Languange Used : en
Release Date : 2002-02-01
Publisher by : Cambridge University Press






Biliary Tract And Gallbladder Cancer


Biliary Tract And Gallbladder Cancer Read Online Download

Author by : Joseph M. Herman
Languange Used : en
Release Date : 2014-03-21
Publisher by : Springer Science & Business Media






Pharmacology Clear Simple


Pharmacology Clear Simple Read Online Download

Author by : Cynthia J Watkins
Languange Used : en
Release Date : 2018-04-18
Publisher by : F.A. Davis






Clinician S Pocket Drug Reference 2008


Clinician S Pocket Drug Reference 2008 Read Online Download

Author by : Leonard G. Gomella
Languange Used : en
Release Date : 2008-03-03
Publisher by : McGraw Hill Professional






Leave a Reply

Your email address will not be published. Required fields are marked *