Pediatric Urinary Tract Infections in a Tertiary Care Center from North India (Report)

Pediatric Urinary Tract Infections in a Tertiary Care Center from North India (Report)

Paediatric urinary tract infections (UTI) are associated with high morbidity and long term complications like renal scarring, hypertension, and chronic renal failure. A cause of occult febrile illness in up to 5 per cent of young children often remains undiagnosed (1), documented in cases associated with vesicoureteral reflux (VUR) (2). Gram negative enteric bacilli, especially Escherichia coli and Klebsiella spp. are the leading pathogens1 though Enterococcus spp., yeasts and Staphylococcus aureus have emerged as prominent agents in recent years (3-5), many of them resistant to multiple antibiotics (3-5). Therapy for these children requires urine culture and appropriate antimicrobial sensitivity testing. Recent studies on paediatric UTI in India are limited. In a retrospective analysis, of the 52 children treated for posterior urethral valves (PUV), 34 had renal scarring (3). A significant correlation was seen between the occurrence of renal scarring and breakthrough UTI (3). UTI in children with symptomatic unilateral pelvi-ureteric junction obstruction (PUJO) was shown to be associated with poor somatic growth in another study from India (5). In the present study, we report the clinical, microbiological, and antimicrobial resistance profile of all consecutive paediatric UTI patients, presented at 304 bed advanced paediatric centre at Postgraduate Institute of Medical Education & Research, Chandigarh, from July to December 2006. Material & Methods

Pediatric Urinary Tract Infections in a Tertiary Care Center from North India (Report)



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