Posaconazole (Noxafil): A New Triazole Antifungal Agent (Pharmacology Notes) (Drug Overview)

Posaconazole (Noxafil): A New Triazole Antifungal Agent (Pharmacology Notes) (Drug Overview)

Posaconazole is the newest triazole antifungal agent. It is structurally related to itraconazole and has activity against Candida species, Aspergillus species, Cryptococcus neoformans, the zygomycetes, and other filamentous fungi. Randomized, double-blind trials have shown posaconazole to be at least as efficacious as fluconazole for the prevention of invasive fungal infections in immunocompromised patients. It has also shown promising results in the treatment of various fungal infections refractory to other antifungal therapy. The dose of posaconazole is 200 mg orally three times daily for the prevention of invasive fungal infections and 800 mg daily in two to four divided doses for the treatment of invasive fungal infections refractory to other antifungal treatment. All posaconazole doses should be given with food or a nutritional supplement to enhance absorption. The most common adverse effects reported with posaconazole therapy were fever, diarrhea, nausea, vomiting, and headache. Instances of elevated liver enzyme levels, hyper-bilirubinemia, and hepatocellular damage were also noted in clinical trials, and these laboratory values should be monitored during treatment with posaconazole. **********

Posaconazole (Noxafil): A New Triazole Antifungal Agent (Pharmacology Notes) (Drug Overview)



Here is Download Link

Pathogenic Yeasts


Pathogenic Yeasts Read Online Download

Author by : Ruth Ashbee
Languange Used : en
Release Date : 2009-10-27
Publisher by : Springer Science & Business Media






Textbook Of Critical Care


Textbook Of Critical Care Read Online Download

Author by : Jean-Louis Vincent
Languange Used : en
Release Date : 2016-11-27
Publisher by : Elsevier Health Sciences






Antifungal Therapy


Antifungal Therapy Read Online Download

Author by : Mahmoud A. Ghannoum, PhD, EMBA
Languange Used : en
Release Date : 2016-04-19
Publisher by : CRC Press






Casebook In Clinical Pharmacokinetics And Drug Dosing


Casebook In Clinical Pharmacokinetics And Drug Dosing Read Online Download

Author by : Henry Cohen
Languange Used : en
Release Date : 2014-10-06
Publisher by : McGraw Hill Professional






Canine And Feline Dermatology Drug Handbook


Canine And Feline Dermatology Drug Handbook Read Online Download

Author by : Sandra N. Koch
Languange Used : en
Release Date : 2012-05-01
Publisher by : John Wiley & Sons






Formulating Poorly Water Soluble Drugs


Formulating Poorly Water Soluble Drugs Read Online Download

Author by : Robert O. Williams III
Languange Used : en
Release Date : 2011-12-04
Publisher by : Springer Science & Business Media






Combating Fungal Infections


Combating Fungal Infections Read Online Download

Author by : Iqbal Ahmad
Languange Used : en
Release Date : 2014-12-13
Publisher by : Springer






Leave a Reply

Your email address will not be published. Required fields are marked *