Primary Hyperparathyroidism and Pregnancy (Case Study)

Primary Hyperparathyroidism and Pregnancy (Case Study)

Primary hyperparathyroidism (PHP) has a prevalence of 0.15%; however, when taking into account the undiscovered cases that are asymptomatic, some have estimated this rate to be as high as 1.4% (1). PHP is the third most common endocrine disorder after diabetes and thyroid disease, and women are affected twice as often as men (2, 3). Most patients suffering from PHP are older than 45 years, but 25% are diagnosed in their childbearing years. Hunter and Turnbull documented the first case of hyperparathyroidism in pregnancy in 1931 (4, 5). It is theorized that the incidence of PHP in the pregnant patient is similar to that in the nonpregnant patient. PHP commonly goes unrecognized due to the physiological changes of pregnancy. Hypoalbuminemia, calcium transport across the placenta, and an increased glomerular filtration rate all contribute to the appearance of lower calcium levels in the pregnant patient. In addition, estrogen is thought to inhibit parathyroid hormone (PTH)-mediated bone resorption, causing a dose-related reduction in serum calcium in pregnancy (6). We present a case of a pregnant patient with chronic hypertension that was exacerbated throughout the course of her pregnancy with a concomitant diagnosis of PHP and its sequelae for both the mother and fetus.

Primary Hyperparathyroidism and Pregnancy (Case Study)



Here is Download Link

A Case Based Guide To Clinical Endocrinology


A Case Based Guide To Clinical Endocrinology Read Online Download

Author by : Terry F. Davies
Languange Used : en
Release Date : 2015-10-22
Publisher by : Springer






Endocrine Secrets


Endocrine Secrets Read Online Download

Author by : Michael T. McDermott
Languange Used : en
Release Date : 2013
Publisher by : Elsevier Health Sciences






Pregnancy And Endocrine Disorders An Issue Of Endocrinology And Metabolism Clinics Of North America


Pregnancy And Endocrine Disorders An Issue Of Endocrinology And Metabolism Clinics Of North America Read Online Download

Author by : Mark E. Molitch
Languange Used : en
Release Date : 2019-07-23
Publisher by : Elsevier Health Sciences






Acute Abdomen During Pregnancy


Acute Abdomen During Pregnancy Read Online Download

Author by : Goran Augustin
Languange Used : en
Release Date : 2014-05-12
Publisher by : Springer






Textbook Of Endocrine Surgery


Textbook Of Endocrine Surgery Read Online Download

Author by : Orlo H Clark
Languange Used : en
Release Date : 2016-02-29
Publisher by : JP Medical Ltd






Obstetrics Normal And Problem Pregnancies E Book


Obstetrics Normal And Problem Pregnancies E Book Read Online Download

Author by : Steven G. Gabbe
Languange Used : en
Release Date : 2016-05-23
Publisher by : Elsevier Health Sciences






Case Presentations In Endocrinology And Diabetes


Case Presentations In Endocrinology And Diabetes Read Online Download

Author by : P. H. Baylis
Languange Used : en
Release Date : 2013-10-22
Publisher by : Butterworth-Heinemann






Leave a Reply

Your email address will not be published. Required fields are marked *