Sildenafil–a Possible Treatment for Acute Pulmonary Hypertension During Cardiac Surgery (Clinical Report)

Sildenafil--a Possible Treatment for Acute Pulmonary Hypertension During Cardiac Surgery (Clinical Report)

Primary pulmonary hypertension has an annual incidence of 1 to 2 cases per million people in the general population and an onset in the third to fourth decades of life (1). It is a progressive disease that affects women twice as frequently as men; the mean survival time from diagnosis is 2.5 years (2). Patients with chronic congestive heart failure may develop secondary pulmonary hypertension, and this may become a limiting factor for acceptance into a cardiac transplantation program. The new cardiac graft will have a normal-sized right ventricle that may fail when exposed to the increased workload of a preexisting elevated pulmonary vascular resistance (PVR). It is vitally important to prevent acute elevations in PVR intraoperatively in patients undergoing cardiac transplantation with marginally acceptable levels of pulmonary hypertension. The mechanisms to treat an acute rise in pulmonary artery pressures in these circumstances are limited. A new therapy being examined for the treatment of primary and secondary pulmonary hypertension is the administration of oral sildenafil (3-5). Sildenafil is a selective vasodilator that prolongs the action of cyclic guanosine monophosphate (cGMP) by selective inhibition of phosphodiesterase (PDE) type 5, of which the lung has a rich supply. This action potentiates the effect of endogenously produced nitric oxide in the lung with resulting pulmonary vasodilatation. This report describes an early experience of administering sildenafil to a patient with pulmonary hypertension and right ventricular dysfunction who was undergoing cardiac transplantation surgery at Baylor University Medical Center.

Sildenafil--a Possible Treatment for Acute Pulmonary Hypertension During Cardiac Surgery (Clinical Report)



Here is Download Link

Sildenafil


Sildenafil Read Online Download

Author by : Udo Dunzendorfer
Languange Used : en
Release Date : 2012-12-06
Publisher by : Birkhäuser






Viagra Sildenafil


Viagra Sildenafil Read Online Download

Author by : Jane McCall
Languange Used : en
Release Date : 2018-03-24
Publisher by : Createspace Independent Publishing Platform






Viagra Sildenafil


Viagra Sildenafil Read Online Download

Author by : Evelyn C. Cortez
Languange Used : en
Release Date : 2018-09-23
Publisher by : Independently Published






Sildenafil 144 Success Secrets 144 Most Asked Questions On Sildenafil What You Need To Know


Sildenafil 144 Success Secrets 144 Most Asked Questions On Sildenafil What You Need To Know Read Online Download

Author by : Nathan Salas
Languange Used : en
Release Date : 2014-12-22
Publisher by : Emereo Publishing






Lady Era 100mg Sildenafil Lady Era 100mg Sildenafil Is Scientifically Formulated To Provide Maximum And Intense Sexual Satisfaction For Women


Lady Era 100mg Sildenafil Lady Era 100mg Sildenafil Is Scientifically Formulated To Provide Maximum And Intense Sexual Satisfaction For Women Read Online Download

Author by : Emily Jones
Languange Used : en
Release Date : 2018-07-14
Publisher by : Independently Published






Sildenafil


Sildenafil Read Online Download

Author by : G. J. Blokdijk
Languange Used : en
Release Date : 2018-01-30
Publisher by :






Viagra Sildenafil


Viagra Sildenafil Read Online Download

Author by : Doctor Herry Blend
Languange Used : en
Release Date : 2018-10-23
Publisher by :






Intensive Care Medicine


Intensive Care Medicine Read Online Download

Author by : Jean-Louis Vincent
Languange Used : en
Release Date : 2009-02-20
Publisher by : Springer Science & Business Media






Identification Of Sildenafil Viagra And Its Metabolite Uk 103 320 In Six Aviation Fatalities


Identification Of Sildenafil Viagra And Its Metabolite Uk 103 320 In Six Aviation Fatalities Read Online Download

Author by :
Languange Used : en
Release Date : 2006
Publisher by :






Sildenafil 4 Sex Men


Sildenafil 4 Sex Men Read Online Download

Author by : Anned Crowny
Languange Used : en
Release Date : 2018-10-20
Publisher by : Createspace Independent Publishing Platform






Leave a Reply

Your email address will not be published. Required fields are marked *