Solubility Tests and the Peripheral Blood Film Method for Screening for Sickle-Cell Disease: A Cost Benefit Analysis (Original Articles) (Clinical Report)

Solubility Tests and the Peripheral Blood Film Method for Screening for Sickle-Cell Disease: A Cost Benefit Analysis (Original Articles) (Clinical Report)

Sickle-cell disease (SCD) is one of the haemoglobinopathies responsible for high morbidity and mortality among neonates in developing countries, including Uganda. (1) It is therefore necessary to establish the most cost-effective screening and intervention programmes to reduce morbidity and mortality among children with SCD. (2) However, most governments in developing countries, including Uganda, cannot fund all the necessary medical programmes because of scarce resources. Cost benefit analyses are therefore performed to determine which programmes or options offer the greatest benefits at the lowest cost. (3,4) While some developing countries such as Jamaica and Ghana have made progress in introducing comprehensive sickle-cell screening programmes, (5,6) the peripheral blood film method for screening for SCD at district health centres has been recommended in Kenya. (7) In Malawi, the most cost-effective haemoglobinopathy testing methods have been recommended to be used at district hospitals. (8)

Solubility Tests and the Peripheral Blood Film Method for Screening for Sickle-Cell Disease: A Cost Benefit Analysis (Original Articles) (Clinical Report)



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