The Relationship Between Gamma-Glutamyl Transferase Levels and Chronic Kidney Disease Among Appalachian Adults (Scientific Article) (Report)

The Relationship Between Gamma-Glutamyl Transferase Levels and Chronic Kidney Disease Among Appalachian Adults (Scientific Article) (Report)

Introduction Serum gamma-glutamyl transferase (GGT), an enzyme responsible for extracellular catabolism of glutathione and a marker of oxidative stress (1) has been shown to be associated with diabetes mellitus (2) and hypertension, (3) which are considered to be independent risk factors for chronic kidney disease (CKD). However, few epidemiological studies have explored the independent relationship […]

Management of HIV-1 Infection in Adults (Pharmacology Notes)

Management of HIV-1 Infection in Adults (Pharmacology Notes)

Despite significant changes made over the past few years in the management of human immunodeficiency virus (HIV), infection with HIV remains a leading cause of death throughout many regions of the world. According to the Joint United Nations Programme on HIV/AIDS 2008 report on the global AIDS epidemic, 30.8 million adults and 2 million children […]

Symptomatic Hyperlactataemia in Adults on Antiretroviral Therapy: A Single-Centre Experience (Original Articles)

Symptomatic Hyperlactataemia in Adults on Antiretroviral Therapy: A Single-Centre Experience (Original Articles)

The use of nucleoside reverse transcriptase inhibitors (NRTIs) in combination with other antiretroviral drugs in a schedule of antiretroviral therapy (ART) is considered standard-of-care for those living with HIV. (1-3) ART has led to significant decreases in morbidity and mortality, compared with untreated HIV-infected patients. This benefit also extends to those in developing countries. (1,2) […]

Pattern & Correlates of Neurocognitive Dysfunction in Asian Indian Adults with Severe Obstructive Sleep Apnoea (Report)

Pattern & Correlates of Neurocognitive Dysfunction in Asian Indian Adults with Severe Obstructive Sleep Apnoea (Report)

Obstructive sleep apnoea (OSA) is characterized by recurrent sleep disruption and hypoxaemia due to collapse of the upper airway during sleep. It is known to be associated with various cognitive defects since its first description. Cognition comprises of the ability to register, remember, develop abstract concepts, plan, decide and foresee. Cognitive areas most frequently reported […]