Vascular Disruptive Agents for the Treatment of Cancer

Vascular Disruptive Agents for the Treatment of Cancer

Tumour survival and growth is critically dependent on an independent blood supply. As such tumour vasculature presents an ideal target for cancer therapy that is widely applicable, accessible and genetically stable rendering it less prone to resistance. Two approaches have been explored for cancer therapy; firstly the prevention of new vessel formation with inhibitors of […]

Prevalence of Drug-Drug Interactions of Antiretroviral Agents in the Private Health Care Sector in South Africa.

Prevalence of Drug-Drug Interactions of Antiretroviral Agents in the Private Health Care Sector in South Africa.

Objectives. Human immunodeficiency virus (HIV) infection can be effectively treated with highly active antiretroviral therapy (HAART), requiring concomitant administration of three to four different agents, often with a high potential for drug-drug interactions (DDIs). This study aimed to determine the prevalence of possible DDIs between antiretrovirals (ARVs) themselves and other drugs. Design. Retrospective drug utilisation […]

Guidelines for Use of Biological Agents in Psoriasis: Commonalities and Differences/Psoriasiste Biyolojik Ajan Kullanim Kilavuzlari: Ortak Noktalar Ve Farkliliklar (Continuing Medical Education/Surekli Egitim) (Report)

Guidelines for Use of Biological Agents in Psoriasis: Commonalities and Differences/Psoriasiste Biyolojik Ajan Kullanim Kilavuzlari: Ortak Noktalar Ve Farkliliklar (Continuing Medical Education/Surekli Egitim) (Report)

Giris Psoriasis, etyolojisinde genetik ve cevresel etmenlerin rol oynadigi, kronik, inflamatuvar immun aracili bir hastalik olup, ulkeden ulkeye ve irklara gore prevalansi %0.5-4.6 arasinda degismektedir (1). Onceleri sadece deriyi ve eklemleri ilgilendiren bir hastalik olarak dusunulurken, son zamanlarda yapilan calismalar isiginda gunumuzde artik, immun aracili ve kardiyovaskuler hastaliklar ile lenfoma ve deri kanserleri gibi onemli […]

Biologic Agents in Psoriasis/Psoriasiste Biyolojik Ajanlar (Continuing Medical Education/Surekli Egitim) (Report)

Biologic Agents in Psoriasis/Psoriasiste Biyolojik Ajanlar (Continuing Medical Education/Surekli Egitim) (Report)

Giris Son yillarda psoriazis immunopatogenezine ait bilgilerin cogalmasi ile bu hastaliga ozgu ve yan etkiler acisindan daha guvenli tedavilerin gelistirilmesine yonelik calismalar da ivme kazanmistir. Genetik muhendisligini kullanan biyoteknolojik yontemler guvenli ve etkin bir tedavi icin gerekli altyapi ve firsati dogurmus; ortaya cikan rekombinan proteinler biyolojik tedavinin temellerini olusturmustur.

U.S. Army Medical Correspondence Course: Microbiology for the Veterinary Specialist - Bacteria, Pathogenicity, Anaerobic, Antibacterial Agents, Sterilization, Foodborne Illness, Food Spoilage, Mold

U.S. Army Medical Correspondence Course: Microbiology for the Veterinary Specialist – Bacteria, Pathogenicity, Anaerobic, Antibacterial Agents, Sterilization, Foodborne Illness, Food Spoilage, Mold

What is the streak plate method? What foods are involved in an outbreak of staphylococcus food poisoning? What type of disease is caused by Bacillus cereus? If you cannot answer these questions now, you will be able to when you have completed this subcourse. For those who already know this material, let it serve as […]

Agents for Treatment of Overactive Bladder: A Therapeutic Class Review (Pharmacology Notes) (Clinical Report)

Agents for Treatment of Overactive Bladder: A Therapeutic Class Review (Pharmacology Notes) (Clinical Report)

Overactive bladder (OAB) is a medical syndrome defined by symptoms of urgency, with or without urge urinary incontinence (any involuntary loss of urine), usually with frequency and nocturia. Although anticholinergic agents have been the first-line treatment for OAB for many years, the efficacious pharmacologic management of this condition has been compromised by concerns regarding tolerability. […]