Basal-Like Breast Carcinoma: A Phenotypically Distinct Entity (Report)

Basal-Like Breast Carcinoma: A Phenotypically Distinct Entity (Report)

Breast cancer is one of the most common human neoplasms, accounting for 22% of all cancers in women worldwide. (1) The incidence rate is higher in North America, Europe, and Australia than in the less developed regions of Africa and Southern and Eastern Asia. Breast cancer is a highly heterogeneous group of cancers, with diversity […]

Protocol for the Examination of Specimens from Patients with Merkel Cell Carcinoma of the Skin.

Protocol for the Examination of Specimens from Patients with Merkel Cell Carcinoma of the Skin.

The College of American Pathologists offers these protocols to assist pathologists in providing clinically useful and relevant information when reporting results of surgical specimen examinations. The College regards the reporting elements in the “Surgical Pathology Cancer Case Summary (Checklist)” portion of the protocols as essential elements of the pathology report. However, the manner in which […]

Improved Filter Method for Urine Sediment Detection of Urothelial Carcinoma by Fluorescence in Situ Hybridization (Report)

Improved Filter Method for Urine Sediment Detection of Urothelial Carcinoma by Fluorescence in Situ Hybridization (Report)

Bladder cancer is the fourth most common cancer in men and the ninth most common in women. (1) In 2007, an estimated 13 750 Americans will die of bladder cancer, and 67 160 new cases are expected, (1) of which 70% to 75% are classified as non-muscle invasive (stage Ta, T1, or Tis). (2,3) Up […]

Combined Large Cell Neuroendocrine Carcinoma and Papillary Serous Carcinoma of the Endometrium with Pagetoid Spread (Case Reports) (Author Abstract) (Report)

Combined Large Cell Neuroendocrine Carcinoma and Papillary Serous Carcinoma of the Endometrium with Pagetoid Spread (Case Reports) (Author Abstract) (Report)

Although mixed endometrial carcinomas with a neuroendocrine component are rare, (1,2) combined neuroendocrine carcinoma and papillary serous carcinoma of the endometrium is even more unusual. (3) We report the first case, to our knowledge, of a mixed large cell neuroendocrine carcinoma and papillary serous carcinoma of the endometrium, which had pagetoid spread of the neuroendocrine […]

Primary Peritoneal Anaplastic Giant Cell Carcinoma: Case Report of an Unusual and Highly Malignant Mullerian Neoplasm (Case Study)

Primary Peritoneal Anaplastic Giant Cell Carcinoma: Case Report of an Unusual and Highly Malignant Mullerian Neoplasm (Case Study)

Primary peritoneal carcinoma (PPC) is a rare tumor and tends to occur in elderly women. (1) Like its ovarian counterpart, the tumor often presents with abdominal distention, pain, and pressure. (1,2) More than 90% of PPCs are papillary serous carcinomas. (1-3) Other much less common types of PPC include clear cell carcinoma, endometrioid carcinoma, mucinous […]

Number of Lymph Nodes Examined and Associated Clinicopathologic Factors in Colorectal Carcinoma (Report)

Number of Lymph Nodes Examined and Associated Clinicopathologic Factors in Colorectal Carcinoma (Report)

Colorectal carcinoma is the second most common cause of cancer deaths in the United States. (1) The most important prognostic factor in colorectal carcinoma is the nodal status at the time of surgical treatment. The 5-year survival rate for stages I and II colorectal carcinomas is greater than 75%. With nodal metastasis, the 5-year survival […]

Protocol for the Examination of Specimens from Patients with Carcinoma of the Urethra.

Protocol for the Examination of Specimens from Patients with Carcinoma of the Urethra.

The College of American Pathologists offers these protocols to assist pathologists in providing clinically useful and relevant information when reporting results of surgical specimen examinations. The College regards the reporting elements in the “Surgical Pathology Cancer Case Summary (Checklist)” portion of the protocols as essential elements of the pathology report. However, the manner in which […]