Circulating Tumor Cells in Melanoma: A Review of the Literature and Description of a Novel Technique.

Circulating Tumor Cells in Melanoma: A Review of the Literature and Description of a Novel Technique.

Melanoma is a prevalent and deadly disease with limited therapeutic options. Current prognostic factors are unable to adequately guide treatment. Circulating tumor cells are a disease-specific factor that can be used as a prognostic variable to guide therapy. Most research to date has focused on identification of circulating tumor cells using various methods, including polymerase […]

Circulating Tumor Cells in Patients Undergoing Surgery for Hepatic Metastases from Colorectal Cancer (Clinical Report)

Circulating Tumor Cells in Patients Undergoing Surgery for Hepatic Metastases from Colorectal Cancer (Clinical Report)

The liver is often the only site of metastatic disease in patients with colorectal cancer, and such patients are considered for local therapies such as liver resection or tumor ablation. The 5-year survival rate for surgically treated patients is approximately 30% (1). Disease recurrence may be related to intraoperative factors such as the shedding of […]

Neural Stem Cells & Supporting Cells--the New Therapeutic Tools for the Treatment of Spinal Cord Injury (Report)

Neural Stem Cells & Supporting Cells–the New Therapeutic Tools for the Treatment of Spinal Cord Injury (Report)

Introduction Stem cells are key players in the development and maintenance of specific mammalian tissues, and their presence has been long established in blood, skin and intestine. A general definition of stem cell is “a cell that is capable of both self renewal and differentiation”. Stem cells are considered multipotent; since they can produces mature […]

Sex Cells

Sex Cells

Unimaginable until the twentieth century, the clinical practice of transferring eggs and sperm from body to body is now the basis of a bustling market. In Sex Cells, Rene Almeling provides an inside look at how egg agencies and sperm banks do business. Although both men and women are usually drawn to donation for financial […]

Cells Are the New Cure

Cells Are the New Cure

The future of medicine is happening now.  Revolutionary new science is providing cures that were considered science fiction just a few years ago—and not with pills, surgery, or radiation, but with human cells.  Promising treatments now in extensive clinical trials could have dramatic impacts on cancer, autoimmune diseases, organ replacement, heart disease, and even aging […]

Clinical Utility of Adjunctive High-Risk Human Papillomavirus DNA Testing in Women with Papanicolaou Test Findings of Atypical Glandular Cells (Report)

Clinical Utility of Adjunctive High-Risk Human Papillomavirus DNA Testing in Women with Papanicolaou Test Findings of Atypical Glandular Cells (Report)

A typical glandular cell (AGC) interpretations (1-2) and screening for glandular cervical neoplasia (3-7) remain some of the major challenges in gynecologic cytopathology. Even though most Papanicolaou (Pap) tests with AGC findings turn out to reflect a variety of underlying benign conditions, (8-10) a significant subset of AGC cases reflect underlying cervical intraepithelial neoplasia (CIN) […]