Prevalence & Potential Significance of Vitamin D Deficiency in Asian Indians (Report)

Prevalence & Potential Significance of Vitamin D Deficiency in Asian Indians (Report)

Studies from our center and other parts of India have drawn attention towards wide prevalence of vitamin D deficiency (VDD) in our country. VDD has been reported in all age groups including toddlers, school children, pregnant women and their neonates and adult males and females residing in rural and urban India. We reviewed implications of […]

Hereditary C1 Esterase Deficiency in a Zulu Kindred (Scientific Letter) (Letter to the Editor)

Hereditary C1 Esterase Deficiency in a Zulu Kindred (Scientific Letter) (Letter to the Editor)

To the Editor: Hereditary angio-oedema is a rare genetic disorder characterised by recurrent episodes of potentially life-threatening angio-oedema. Despite the apparent absence of variation in incidence among ethnic groups, this is the first reported series in a sub-Saharan African family, and it is likely that the disease remains largely undiagnosed in southern Africa. Although cost […]

Mild Transcobalamin I (Haptocorrin) Deficiency and Low Serum Cobalamin Concentrations (Hematology) (Clinical Report)

Mild Transcobalamin I (Haptocorrin) Deficiency and Low Serum Cobalamin Concentrations (Hematology) (Clinical Report)

Serum cobalamin concentrations are frequently below the reference interval in patients who have no obvious causes for such low concentrations, and it is often not clear what should be done about them (1, 2). Only one-half or fewer of low cobalamin concentrations are explained by malabsorption of either free or food-bound cobalamin, and dietary insufficiency […]

Vitamin D Deficiency in Breastfed Infants & the Need for Routine Vitamin D Supplementation (Commentary)

Vitamin D Deficiency in Breastfed Infants & the Need for Routine Vitamin D Supplementation (Commentary)

There has been increasing global interest regarding the role of vitamin D in health and disease. In fact, more and more scientific evidence linking vitamin D to various chronic diseases in children and adults is emerging. Prevention of vitamin D deficiency and achieving adequate intake of vitamin D and calcium throughout childhood may reduce the […]

Iodine Deficiency Disorders After a Decade of Universal Salt Iodization in a Severe Iodine Deficiency Region in China (Report)

Iodine Deficiency Disorders After a Decade of Universal Salt Iodization in a Severe Iodine Deficiency Region in China (Report)

Iodine is an essential ingredient for the synthesis of thyroid hormones. Iodine deficiency (ID) causes goiter and different forms of physical and mental retardation. Iodine deficiency disorders (IDD) affect the poor, pregnant woman and preschool children (1,2). Normal levels of thyroid hormones are required for neuronal migration and myelination of the foetal brain, and lack […]

Vitamin D Deficiency in Exclusively Breast-Fed Infants (Clinical Report)

Vitamin D Deficiency in Exclusively Breast-Fed Infants (Clinical Report)

Exclusive breast-feeding is recommended up to 6 months of age with all its beneficial effects on child survival. Several studies have concluded that adequate intake of vitamin D cannot be met with human milk as the sole source of vitamin D. As breast-feeding rates increase, the incidence of vitamin D deficiency rickets is also expected […]