Optimal Use of Myco/F Lytic and Standard BACTEC Blood Culture Bottles for Detection of Yeast and Mycobacteria (Report)

Optimal Use of Myco/F Lytic and Standard BACTEC Blood Culture Bottles for Detection of Yeast and Mycobacteria (Report)

Specific media for isolation of fungi and mycobacteria have been introduced on a number of automated blood culture systems; however, their optimal use in a clinical setting is not well defined. In the BACTEC 9240 system (BD Diagnostics, Sparks, Md), the Myco/F Lytic blood culture medium supports the growth of yeast, filamentous fungi, and mycobacteria […]

Frequent Detection of Androgen Receptors in Spindle Cell Lipomas: An Explanation for This Lesion's Male Predominance?(Report)

Frequent Detection of Androgen Receptors in Spindle Cell Lipomas: An Explanation for This Lesion’s Male Predominance?(Report)

Spindle cell lipomas (SCLs) are benign lesions that characteristically occur in the upper back or posterior neck area. Interestingly, more than 90% of SCLs occur in males, a clear male predominance. Ordinary lipomas, which have a female predominance, have an identified putative molecular mechanism for development–a point mutation in a mitochondrial gene. (1) During the […]

Comparison of Fungal Culture Versus Surgical Pathology Examination in the Detection of Histoplasma in Surgically Excised Pulmonary Granulomas (Report)

Comparison of Fungal Culture Versus Surgical Pathology Examination in the Detection of Histoplasma in Surgically Excised Pulmonary Granulomas (Report)

Histoplasma capsulatum is a thermally dimorphic fungus that is found in a wide geographic distribution, but in the United States most commonly infects those living in the Mississippi and Ohio river valleys. H capsulatum (henceforth referred to simply as Histoplasma) is found in the environment, particularly soil enriched with bat and bird droppings, and exposure […]

Improved Filter Method for Urine Sediment Detection of Urothelial Carcinoma by Fluorescence in Situ Hybridization (Report)

Improved Filter Method for Urine Sediment Detection of Urothelial Carcinoma by Fluorescence in Situ Hybridization (Report)

Bladder cancer is the fourth most common cancer in men and the ninth most common in women. (1) In 2007, an estimated 13 750 Americans will die of bladder cancer, and 67 160 new cases are expected, (1) of which 70% to 75% are classified as non-muscle invasive (stage Ta, T1, or Tis). (2,3) Up […]

Evaluation of the Diagnostic Accuracy of Serology Test Kit for Detection of H.Pylori Infection in Patients Presenting With Nonulcer Dyspepsia Taking Histopathology As Gold Standard (Helicobacter Pylori) (Report)

Evaluation of the Diagnostic Accuracy of Serology Test Kit for Detection of H.Pylori Infection in Patients Presenting With Nonulcer Dyspepsia Taking Histopathology As Gold Standard (Helicobacter Pylori) (Report)

Byline: Gohar Ali Khan, Shahila Jaleel, Sarah Riaz and Bilquis A Suleman ABSTRACT

In Situ Detection of Inflammatory Cytokines and Apoptosis in Pemphigus Foliaceus Patients (Report)

In Situ Detection of Inflammatory Cytokines and Apoptosis in Pemphigus Foliaceus Patients (Report)

Endemic pemphigus foliaceus (EPF), or fogo selvagem, is a chronic autoimmune disease (1)fc characterized by the formation of intraepidermal blisters, which are attributed to the presence of immunoglobulin G4 (IgG4) and IgG1 autoantibodies against desmoglein 1 (2) that reduce the adhesion between keratinocytes. (3) In addition to the presence of autoantibodies, a high production of […]