Unlock Your Muscle Gene

Unlock Your Muscle Gene

Provocatively written yet grounded in science, Unlock Your Muscle Gene is a revolutionary guide to physical transformation and the latest information on muscle conditioning, weight loss, and anti-aging strategies. According to Ori Hofmekler, we need to learn how to trigger the genes that retain and develop our muscles and extend our lives—we need to unleash […]

The Sports Gene

The Sports Gene

In high school, I wondered whether the Jamaican Americans who made our track team so successful might carry some special speed gene from their tiny island. In college, I ran against Kenyans, and wondered whether endurance genes might have traveled with them from East Africa. At the same time, I began to notice that a […]

Taq1b Polymorphism of Cholesteryl Ester Transfer Protein (CETP) Gene in Primary Combined Hyperlipidaemia (Report)

Taq1b Polymorphism of Cholesteryl Ester Transfer Protein (CETP) Gene in Primary Combined Hyperlipidaemia (Report)

Background & objectives: Cholesteryl ester transfer protein (CETP) gene polymorphism is known to be associated with changes in lipid profiles. Primary hyperlipidaemia is considered to be a major risk factor for pancreatitis, atherosclerosis and coronary heart disease. We investigated the association of one common polymorphism in the CETP gene (Taqlb) with plasma lipid levels and […]

TPMT Gene Polymorphisms: On the Doorstep of Personalized Medicine (Commentary)

TPMT Gene Polymorphisms: On the Doorstep of Personalized Medicine (Commentary)

Since the initial human genome sequence has become available in 2001, sequence variability among individual genomes came into focus of the research in the field of human genetics. More than 99 per cent of the DNA sequence is identical among individuals. The remaining DNA is responsible for genetic diversity (1). Polymorphisms are common genetic variations […]

Possible Aggravating Impact of Gene Polymorphism in Women with Endometriosis (Report)

Possible Aggravating Impact of Gene Polymorphism in Women with Endometriosis (Report)

Background & objectives: Endometriosis is one of the most commonly encountered benign problems in gynaecology. It is frequently associated with chronic pelvic pain, dysmenorrhoea, menorrhagia and dyspareunia, which lead to infertility. To determine the possible association between polychlorinated biphenyls (PCBs) and GSTM1 null (*0/*0) mutation and their possible impact in the pathogenesis of endometriosis. Methods: […]

Association of Serotonin Transporter Gene Polymorphisms with Obsessive-Compulsive Disorder (OCD) in a South Indian Population (Report)

Association of Serotonin Transporter Gene Polymorphisms with Obsessive-Compulsive Disorder (OCD) in a South Indian Population (Report)

Obsessive compulsive disorder (OCD) is the fourth most prevalent psychiatric disorder with a lifetime prevalence of 2-3 per cent (1). It is often a chronic illness characterized by obsessional thoughts and/or compulsive acts (2). Although OCD is often considered a unitary disorder, there is evidence that it is a heterogeneous disorder (3). Juvenile OCD and […]