The Impact of HIV/AIDS on Blood Transfusion Practice in South Africa: Some Ethical Issues (Original Articles) (Human Immunodeficiency Virus) (Acquired Immune Deficiency Syndrome)

The Impact of HIV/AIDS on Blood Transfusion Practice in South Africa: Some Ethical Issues (Original Articles) (Human Immunodeficiency Virus) (Acquired Immune Deficiency Syndrome)

Blood transfusion has become an essential component of modern medical practice. However, worldwide epidemics of viral diseases–in particular, HIV/AIDS–have made the practice of blood transfusion therapy hazardous, motivating scientists to devise techniques and strategies to ensure the supply of safe blood and blood components for clinical use. The challenges are particularly great in sub-Saharan Africa, […]

Opportunistic Parasitic Infections in HIV/AIDS Patients Presenting with Diarrhoea by the Level of Immunesuppression (Report)

Opportunistic Parasitic Infections in HIV/AIDS Patients Presenting with Diarrhoea by the Level of Immunesuppression (Report)

Background & objectives: Enteric parasites are major cause of diarrhoea in HIV infected individuals. The present study was undertaken to detect enteric parasites in HIV infected patients with diarrhoea at different levels of immunity. Methods: The study was carried out at National AIDS Research Institute, Pune, India, between March 2002 and March 2007 among consecutively […]

HIV/AIDS Influences Blood and Blood Product Use at Groote Schuur Hospital, Cape Town (Original Articles) (Report)

HIV/AIDS Influences Blood and Blood Product Use at Groote Schuur Hospital, Cape Town (Original Articles) (Report)

Human immunodeficiency virus (HIV) infection is associated with cytopenias of all major blood cell lines. Anaemia occurs in up to 70% of patients with HIV/AIDS, and thrombocytopenia, neutropenia or lymphopenia in 40 – 70%. (1) The incidence and severity of cytopenias correlate directly with the degree of immunosuppression, while isolated haematological abnormalities, particularly anaemia and […]

Zidovudine-Induced Anaemia in HIV/AIDS (Commentary) (Report)

Zidovudine-Induced Anaemia in HIV/AIDS (Commentary) (Report)

Several studies have shown that the prevalence of anaemia is high in patients with human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS) (1,2). Anaemia in HIV infection is associated with uniformly adverse outcomes such as opportunistic infections and neurologic deterioration and progression to AIDS (2). Anaemia is associated with several other consequences including […]

Common Mental Disorders in People Living with HIV/AIDS (CLINICAL: Overview) (Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome) (Report)

Common Mental Disorders in People Living with HIV/AIDS (CLINICAL: Overview) (Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome) (Report)

In South Africa, depressive and anxiety disorders are common in the general population. According to the World Health Organization-led South African Stress and Health (SASH) study, the 12-month prevalence of depressive and anxiety disorders (combined) was 12.6%,4 while the lifetime prevalence of these disorders was 25.6%.5 Similarly, the SASH study found a 12-month prevalence of […]