Cryptococcal meningitis (CM) is a major cause of death among HIV-infected individuals. It causes an estimated 957 900 cases and 624 700 deaths worldwide annually, the vast majority of them in sub-Saharan Africa. (1) In Cape Town, CM is now the most common cause of adult meningitis (63% of all microbiologically confirmed cases (2)), and […]
Tuberculosis (TB) remains one of the most important opportunistic infections among HIV-infected patients. Diagnosing pulmonary TB (PTB) has become problematic because HIV-positive patients tend to be smear negative and smear microscopy is the first line of diagnosis in people suspected to have TB. (1) It is estimated that more than 50% of HIV-infected patients will […]
Background. Chronic otorrhoea occurs commonly in HIVinfected children. However, there are few data on incidence and severity. Objective. To document the prevalence of otorrhoea in the clinic attendees.
A balanced colonisation by endogenous vaginal microflora of the lower female genital tract consists of predominantly Lactobacillus species, (1) co-existing with vaginal anaerobes and aerobes such as Streptococcus agalactiae (e.g. group B streptococci) (2) and the Bacteroides family. (3) Disturbing this microbial milieu results in overgrowth of bacterial vaginosis-related organisms which are associated with a […]
The life saving benefits of highly active antiretroviral therapy (HAART) for the treatment of HIV infection have been well documented (1). HAART needs very high levels of adherence to be effective and to prevent appearance of viral mutations related with resistance (2,3). Despite a lack of corroborative evidence, specific concerns have been raised regarding the […]
Cervical cancer is the most common cancer among South African women. The age-standardised mortality rate from cervical cancer is 21.0% in South Africa but only 8.9% worldwide. (1,2) This differential highlights inequality in the availability of screening for easily treated precursor lesions. South Africa’s cervical cancer burden severity is compounded by its HIV epidemic (2008 […]