Emergence of Drug Resistant Mutations After Single Dose Nevirapine Exposure in HIV-1 Infected Pregnant Women in South India (Report)

Emergence of Drug Resistant Mutations After Single Dose Nevirapine Exposure in HIV-1 Infected Pregnant Women in South India (Report)

In India, HIV prevalence among pregnant women is reported to be 0.3 per cent (1). HIV transmission from mother to child can occur in utero, intrapartum (during labour) or postpartum (through breastfeeding). In the absence of any interventions, about 25-30 per cent of infants will be infected with HIV. Several regimens have been tested for […]

Prevalence of Metabolic Syndrome in Psychiatric Inpatients in a Tertiary Care Centre in North India (Report)

Prevalence of Metabolic Syndrome in Psychiatric Inpatients in a Tertiary Care Centre in North India (Report)

Metabolic syndrome (MS) is a complex disorder characterized by central obesity, dyslipidaemia, abnormal glucose tolerance and hypertension (1). Its pathophysiology remains obscure but it has been hypothesized to involve insulin resistance and a proinflammatory state (2,3). A survey on MS in the United States reported the prevalence at 24 per cent in adults, and found […]

Identification of Anopheles Fauna in a Hyperendemic Falciparum Area of Orissa State, India (Report)

Identification of Anopheles Fauna in a Hyperendemic Falciparum Area of Orissa State, India (Report)

Background & objectives: Keonjhar district of Orissa State has been hyperendemic for falciparum malaria since many years with alarming deaths due to cerebral malaria, Therefore an entomological investigation to know more about the relative prevalence of Anopheles species was done. Methods: Daytime indoor resting and outdoor resting, light trap and double bed net collections were […]

Analysis of the Risk Factors Predisposing to Fungal, Bacterial & Acanthamoeba Keratitis in South India (Report)

Analysis of the Risk Factors Predisposing to Fungal, Bacterial & Acanthamoeba Keratitis in South India (Report)

Corneal diseases, especially infective keratitis, are a major cause of vision loss and blindness second only to cataract (1). A study from south India reported that the incidence of corneal infections in India is almost 10 times that reported in the United States (2). This is likely to be the case in other developing countries […]

Cytogenetic Study of Myelodysplastic Syndrome from India (Report)

Cytogenetic Study of Myelodysplastic Syndrome from India (Report)

Background & objectives: Myelodysplastic syndrome (MDS) represents a group of clonal haematological disorders characterized by progressive cytopenia reflecting defects in erythroid, myeloid and megakaryocytic maturation. The incidence of MDS is more in older age groups and frequent chromosome abnormalities reported to be monosomies 5 and 7. However, the data on cytogenetic changes in Indian MDS […]

Spectrum of Haemoglobinopathies Diagnosed by Cation Exchange-Hplc & Modulating Effects of Nutritional Deficiency Anaemias from North India (Report)

Spectrum of Haemoglobinopathies Diagnosed by Cation Exchange-Hplc & Modulating Effects of Nutritional Deficiency Anaemias from North India (Report)

The laboratory diagnosis of thalassaemias and other haemoglobinopathies can be achieved by a step-wise approach starting with a detailed clinical history, thorough haematologic evaluation [including haemoglobin level, complete blood count (CBC), reticulocyte count, and red blood cell (RBC) morphology], protein based analytic methods [alkaline and acid Hb-electrophoresis, isoelectric focusing (IEF) and high performance liquid chromatography […]