Precursor Lymphoblastic Lymphoma Reoccurring As a Donor-Derived Neoplasm: A Case Report and Review of the Literature (Case Reports) (Report)

Precursor Lymphoblastic Lymphoma Reoccurring As a Donor-Derived Neoplasm: A Case Report and Review of the Literature (Case Reports) (Report)

Posttransplant lymphoproliferative disorder (PTLD) encompasses a heterogeneous group of diseases characterized by lymphoid proliferation or lymphoma occurring as a result of immunosuppression in solid organ or bone marrow allograft transplant recipients. (1) Lesions arising less than 1 year posttransplantation are predominantly attributable to genomic integration of Epstein-Barr virus (EBV); by contrast, lesions occurring late after […]

Relevance of Specific Immunoglobulin M and Immunoglobulin G for Parvovirus B19 Diagnosis in Patients with Acute Lymphoblastic Leukemia Receiving Chemotherapy: Prospective Study (Clinical Report)

Relevance of Specific Immunoglobulin M and Immunoglobulin G for Parvovirus B19 Diagnosis in Patients with Acute Lymphoblastic Leukemia Receiving Chemotherapy: Prospective Study (Clinical Report)

Parvovirus B19 (PB19) virion has a simple structure composed of only 2 proteins and a linear, single-stranded DNA molecule. The nonenveloped viral particles are 22 to 24 nm in diameter and show icosahedral symmetry, and often both empty and full capsids are visible by negative staining and electron microscopy. (1) Children are probably at highest […]

An Investigation of General and High-Level Language Skills in Children Treated with Central Nervous System-Targeted Chemotherapy for Acute Lymphoblastic Leukemia (Report)

An Investigation of General and High-Level Language Skills in Children Treated with Central Nervous System-Targeted Chemotherapy for Acute Lymphoblastic Leukemia (Report)

Keywords: Childhood acute lymphoblastic leukemia; CNS-targeted chemotherapy; intrathecal methotrexate; general language skills; high-level language skills The general language skills of 13 children (mean age, 8.2 years) treated with a central nervous system (CNS)-targeted chemotherapeutic regimen for acute lymphoblastic leukemia (ALL) and 13 control children matched on age, sex, and educational level were assessed using the […]