To the Editor: Cryptococcal meningitis (CM) remains a serious cause of mortality and morbidity in individuals infected with the human immunodeficiency virus (HIV). The optimal treatment of CM is unknown. We conducted a systematic review to determine the best treatment for CM with an emphasis on resource-poor settings. Six studies met the inclusion criteria; none […]
SUMMARY We aimed to evaluate the diagnostic value of lumbar puncture in excluding nosocomial meningitis as the cause of mental status changes in medical intensive care unit patients. We retrospectively reviewed the records of all patients admitted to the medical intensive care unit at our institution over a four-year period who had a lumbar puncture […]
Introduction Haemophilus influenzae has long been recognised as a cause of serious infections (i.e., pneumonia and meningitis) and mortality in children less than 5 yr old. Prior to the introduction of H. influenzae type b (Hib) immunization, the incidence of invasive Hib infection was 20-50/100,000 children 5 yr of age in industrialized countries and higher […]
Cryptococcal meningitis (CM) is now the most common cause of adult meningitis in southern Africa (1,2) and is a major burden on local health care services. (3) Treatment remains unsatisfactory, with acute mortality in Africa ranging from 30% to 50%, even with optimal therapy. (4,5) Consequently, CM is a major cause of mortality in African […]
INTRODUCTION Bacterial meningitis is one of the most potentially serious infections occurring in infants and older children and is associated with a high incidence of acute complications and risk of long-term morbidity (1). Systemic bacterial infections are known by the generic term neonatal sepsis which incorporates septicaemia, pneumonia and meningitis of the new born. Neonatal […]
