Management of Cryptoccocal Meningitis in Resource-Limited Settings: A Systematic Review (Scientific Letters) (Clinical Report)

Management of Cryptoccocal Meningitis in Resource-Limited Settings: A Systematic Review (Scientific Letters) (Clinical Report)

To the Editor: Cryptococcal meningitis (CM) remains a serious cause of mortality and morbidity in individuals infected with the human immunodeficiency virus (HIV). The optimal treatment of CM is unknown. We conducted a systematic review to determine the best treatment for CM with an emphasis on resource-poor settings. Six studies met the inclusion criteria; none […]

The Yield of Lumbar Puncture to Exclude Nosocomial Meningitis As Aetiology for Mental Status Changes in the Medical Intensive Care Unit.

The Yield of Lumbar Puncture to Exclude Nosocomial Meningitis As Aetiology for Mental Status Changes in the Medical Intensive Care Unit.

SUMMARY We aimed to evaluate the diagnostic value of lumbar puncture in excluding nosocomial meningitis as the cause of mental status changes in medical intensive care unit patients. We retrospectively reviewed the records of all patients admitted to the medical intensive care unit at our institution over a four-year period who had a lumbar puncture […]

Multi-Center Surveillance for Pneumonia & Meningitis Among Children (2 Yr) for Hib Vaccine Probe Trial Preparation in India (Report)

Multi-Center Surveillance for Pneumonia & Meningitis Among Children (2 Yr) for Hib Vaccine Probe Trial Preparation in India (Report)

Introduction Haemophilus influenzae has long been recognised as a cause of serious infections (i.e., pneumonia and meningitis) and mortality in children less than 5 yr old. Prior to the introduction of H. influenzae type b (Hib) immunization, the incidence of invasive Hib infection was 20-50/100,000 children 5 yr of age in industrialized countries and higher […]

Symptomatic Relapse of Hiv-Associated Cryptococcal Meningitis in South Africa: The Role of Inadequate Secondary Prophylaxis (Original Articles) (Clinical Report)

Symptomatic Relapse of Hiv-Associated Cryptococcal Meningitis in South Africa: The Role of Inadequate Secondary Prophylaxis (Original Articles) (Clinical Report)

Cryptococcal meningitis (CM) is now the most common cause of adult meningitis in southern Africa (1,2) and is a major burden on local health care services. (3) Treatment remains unsatisfactory, with acute mortality in Africa ranging from 30% to 50%, even with optimal therapy. (4,5) Consequently, CM is a major cause of mortality in African […]

Antimicrobial Sensitivity Pattern of Gram Positive CSF Isolates in Children with Septic Meningitis in a Tertiary Care Hospital (Original Work) (Report)

Antimicrobial Sensitivity Pattern of Gram Positive CSF Isolates in Children with Septic Meningitis in a Tertiary Care Hospital (Original Work) (Report)

INTRODUCTION Bacterial meningitis is one of the most potentially serious infections occurring in infants and older children and is associated with a high incidence of acute complications and risk of long-term morbidity (1). Systemic bacterial infections are known by the generic term neonatal sepsis which incorporates septicaemia, pneumonia and meningitis of the new born. Neonatal […]