Ximelagatran (Exanta): Alternative to Warfarin?(Pharmacology Notes) (Drug Overview)

Ximelagatran (Exanta): Alternative to Warfarin?(Pharmacology Notes) (Drug Overview)

For decades, the standards of antithrombotic therapy have been heparin and coumarin compounds, primarily warfarin (1). Other newer approaches include low-molecular-weight heparins, fondaparinux, lepirudin, argatroban, and melagatran (investigational). Although existing treatments are effective, they have many limitations. A safer, more convenient therapy is needed. Ximelagatran is the first oral treatment in a new World Health […]

Darbepoetin Alfa (Aranesp) (Pharmacology Notes) (Drug Overview)

Darbepoetin Alfa (Aranesp) (Pharmacology Notes) (Drug Overview)

The Food and Drug Administration (FDA) approved darbepoetin alfa (Aranesp) for treatment of anemia as sociated with chronic renal failure (CRF) in patients on dialysis and patients not on dialysis (1). The manufacturer of the drug also filed an application with the FDA on September 18, 2001, to receive an indication for treatment of anemia […]

Standing in the Gap: The Primary Care Physician and Alzheimer's Disease (Scientific Article: Special Issue) (Disease/Disorder Overview)

Standing in the Gap: The Primary Care Physician and Alzheimer’s Disease (Scientific Article: Special Issue) (Disease/Disorder Overview)

Introduction An astonishing volume of material has been published about Alzheimer’s disease in recent years. Typing the word “Alzheimer’s” into Google will reward you with 13,600,000 “results” in 0.15 seconds, and a PubMed search of the same instantly yields over 55,000 journal articles. Yet, primary care physicians (PCPs) who regularly see patients with Alzheimer’s and […]

Disclosure of Personal Information (Medicolegal Issues) (Law Overview)

Disclosure of Personal Information (Medicolegal Issues) (Law Overview)

It is well known that personal information, such as health care records, is privileged. As discussed last issue, the federal government has recently taken additional steps to ensure that the privileged nature of this information is maintained. Financial information is also guarded and maintained as personal and private. It is also well known that in […]