Nickel, Its Adverse Health Effects & Oxidative Stress (Clinical Report)

Nickel, Its Adverse Health Effects & Oxidative Stress (Clinical Report)

Nickel-induced toxicity and carcinogenicity, with an emphasis on the generation and role of reactive oxygen species is reviewed. Nickel is a known haematotoxic, immunotoxic, neurotoxic, genotoxic, reproductive toxic, pulmonary toxic, nephrotoxic, hepatotoxic and carcinogenic agent. This article presents a selective review on nickel and effect of its acute, subchronic and chronic doses on certain metabolically […]

Attenuation of Oxidative Stress & DNA Damage in Varicocelectomy: Implications in Infertility Management (Report)

Attenuation of Oxidative Stress & DNA Damage in Varicocelectomy: Implications in Infertility Management (Report)

Varicocele is one of the commonest surgically reversible causes of infertility and affects about 40 per cent males with primary infertility and 70-80 per cent males with secondary infertility. The pathophysiology of varicocele induced infertility remains unknown. One of the mechanisms by which it causes a decline in semen quality is increased testicular temperature due […]

Oxidative Stress & Male Infertility (Report)

Oxidative Stress & Male Infertility (Report)

The male factor is considered a major contributory factor to infertility. Apart from the conventional causes for male infertility such as varicocoele, cryptorchidism, infections, obstructive lesions, cystic fibrosis, trauma, and tumours, a new and important cause has been identified: oxidative stress. Oxidative stress is a result of the imbalance between reactive oxygen species (ROS) and […]

Association of Changes in Oxidative and Proinflammatory States with Changes in Vascular Function After a Lifestyle Modification Trial Among Obese Children (Lipids, Lipoproteins, And Cardiovascular Risk Factors)

Association of Changes in Oxidative and Proinflammatory States with Changes in Vascular Function After a Lifestyle Modification Trial Among Obese Children (Lipids, Lipoproteins, And Cardiovascular Risk Factors)

The prevalence of childhood obesity and its consequences are increasing rapidly in low- and middle-income countries (1). It is well documented that childhood obesity tracks into adulthood. Of special concern are the cardiometabolic consequences of obesity, especially hypertension, dyslipidemia, and impaired glucose metabolism, that are already present in young children of different ethnicities (2, 3). […]