The Role of Neurotransmitters in IBS Pathophysiology: A Literature Review (Under Grad) (Irritable Bowel Syndrome)

The Role of Neurotransmitters in IBS Pathophysiology: A Literature Review (Under Grad) (Irritable Bowel Syndrome)

Objective: To determine if neurotransmitters have relevance in the pathology of irritable bowel syndrome (IBS). Review methods: Electronic searches of literature from PUBMED, MEDLINE and EBSCO in October and November 2006 using the terms IBS, neurotransmitters, serotonin, CCK, mast cell, 5-HT, substance P. Some of the articles were only published in abstract form.

Emerging Therapies Targeting the Pathophysiology of Sickle Cell Disease

Emerging Therapies Targeting the Pathophysiology of Sickle Cell Disease

This issue of Hematology/Oncology Clinics, guest edited by Dr. Elliott Vichinsky, is devoted to Sickle Cell Disease, and focuses on pathophysiology of hemoglobinopathies, therapeutic targets, and new approaches to correcting ineffective erythropoiesis and iron dysregulation. Articles in this issue include Polymerization and red cell membrane changes; Overview on reperfusion injury in the pathophysiology of SCD; […]