Objective: To determine if neurotransmitters have relevance in the pathology of irritable bowel syndrome (IBS). Review methods: Electronic searches of literature from PUBMED, MEDLINE and EBSCO in October and November 2006 using the terms IBS, neurotransmitters, serotonin, CCK, mast cell, 5-HT, substance P. Some of the articles were only published in abstract form.
Understanding pathophysiology is the first step toward clinical medicine. This book presents the most important mechanisms of how disease develops in nearly 200 vivid color plates accompanied by clear text. Every double page, with text on the left and pictures on the right, gives a rapid and complete overview of its topic. The contents are […]
This is the 13th edition of a book written for students and specialists who are interested in developing a fundamental understanding of pathology and treatment of hematologic diseases. The amount of knowledge required by hematologists to identify the best course of treatment for a patient in this field is changing rapidly and has fueled an […]
This issue of Hematology/Oncology Clinics, guest edited by Dr. Elliott Vichinsky, is devoted to Sickle Cell Disease, and focuses on pathophysiology of hemoglobinopathies, therapeutic targets, and new approaches to correcting ineffective erythropoiesis and iron dysregulation. Articles in this issue include Polymerization and red cell membrane changes; Overview on reperfusion injury in the pathophysiology of SCD; […]