Postoperative Glycemic Control in Cardiac Surgery Patients (Pharmacology Notes) (Report)

Postoperative Glycemic Control in Cardiac Surgery Patients (Pharmacology Notes) (Report)

Blood glucose management in critically ill patients remains an ongoing controversy. In recent years, clinical trials evaluating blood glucose control in critically ill patients advocated for intense blood glucose management, with target blood glucose levels between 80 and 110 mg/dL (1). Intense blood glucose control resulted in a reduction in morbidity and mortality in the […]

Eszopiclone (Lunesta): A New Nonbenzodiazepine Hypnotic Agent (Pharmacology Notes) (Drug Overview)

Eszopiclone (Lunesta): A New Nonbenzodiazepine Hypnotic Agent (Pharmacology Notes) (Drug Overview)

Randomized, placebo-controlled trials have shown that eszopiclone, a newly available nonbenzodiazepine hypnotic, effectively treats the symptoms of insomnia. Its pharmacokinetic and pharmacodynamic parameters are similar to those of the other currently available nonbenzodiazepine hypnotics (i.e., zolpidem and zaleplon). The unique quality of eszopiclone lies in its product labeling. It is not restricted to short-term use, […]

Ibuprofen Lysine (Neoprofen) for the Treatment of Patent Ductus Arteriosus (Pharmacology Notes)

Ibuprofen Lysine (Neoprofen) for the Treatment of Patent Ductus Arteriosus (Pharmacology Notes)

Patent ductus arteriosus (PDA) affects approximately 31% of infants whose birth weight is between 501 and 1500 g. The ductus arteriosus is a blood vessel that allows blood to bypass the pulmonary vasculature in utero. Oxygen delivery and elimination of prostaglandins are essential for the closure of the ductus after birth. For years, indomethacin has […]

Medical Pharmacology and Therapeutics

Medical Pharmacology and Therapeutics

The fourth edition of Medical Pharmacology and Therapeutics provides a complete basis for learning about safe and effective prescribing of modern medicines. It offers all the pharmacology medical students will need – from basic science pharmacology and pathophysiology, through to clinical pharmacology and therapeutics, in line with today’s integrated curricula. The disease-based approach and clear […]