Some Hematological Parameters and the Prognostic Value of CD4, CD8 and Total Lymphocyte Counts and CD4/CD8 Cell Count Ratio in Healthy HIV Sero-Negative, Healthy HIV Sero-Positive and AIDS Subjects in Port Harcourt, Nigeria/Nijerya'da (Port Harcourt) Saglikli HIV Seronegatif, Saglikli HIV Seropozitif Ve AIDS Hastasi Olgularda CD4, CD8 Ve Toplam Lenfosit Sayimi Ve CD4/CD8 ... (Research Article) (Cluster of Differentiation) (Human Immunodeficiency Virus) (Acquired Immunodeficiency Syndrome) (Report)

Some Hematological Parameters and the Prognostic Value of CD4, CD8 and Total Lymphocyte Counts and CD4/CD8 Cell Count Ratio in Healthy HIV Sero-Negative, Healthy HIV Sero-Positive and AIDS Subjects in Port Harcourt, Nigeria/Nijerya’da (Port Harcourt) Saglikli HIV Seronegatif, Saglikli HIV Seropozitif Ve AIDS Hastasi Olgularda CD4, CD8 Ve Toplam Lenfosit Sayimi Ve CD4/CD8 … (Research Article) (Cluster of Differentiation) (Human Immunodeficiency Virus) (Acquired Immunodeficiency Syndrome) (Report)

Introduction Since its identification in 1981, human immunodeficiency virus (HIV) infection and the associated acquired immunodeficiency syndrome (AIDS) remain a major health burden globally. Recent estimates indicate that over 35 million people are affected worldwide, with mortality counts of over 20 million [1]. About 70% of these deaths have occurred in sub-Saharan Africa [1], where […]

Prognostic Factors in Gastric Cancer Using Log-Normal Censored Regression Model (Report)

Prognostic Factors in Gastric Cancer Using Log-Normal Censored Regression Model (Report)

Background & objectives: Gastric cancer is one of the most common cancers in the world. It is rarely detected early, and the prognosis remains poor. Cox proportional hazard model is used to examine the relationship between survival and covariates. Parametric survival models such as log normal regression model can also be used for this analysis. […]

Gene Expression-Based Prognostic and Predictive Markers for Breast Cancer: A Primer for Practicing Pathologists (Report)

Gene Expression-Based Prognostic and Predictive Markers for Breast Cancer: A Primer for Practicing Pathologists (Report)

CLINICAL BACKGROUND The identification of molecular markers with prognostic significance may help cancer patients avoid treatment that is unlikely to be successful. In breast cancer, for example, clinical studies have shown that adding adjuvant chemotherapy to tamoxifen in the treatment of node-negative, hormone receptor (HR)-positive breast cancer improves disease outcome. (1) However, treatment with tamoxifen […]