Hematological Indices in an Older Population Sample: Derivation of Healthy Reference Values (Hematology) (Survey)

Hematological Indices in an Older Population Sample: Derivation of Healthy Reference Values (Hematology) (Survey)

Laboratory-based investigations are subject to substantial variability arising from several sources, including differences between subjects (e.g., age, sex, and genetic variation), within-subject variation (e.g., circadian change and pathological change), variations in sample collection and handling, and laboratory measurement error [1]. In interpreting an individual patient’s laboratory test results, the clinician usually compares the reported values […]

Poverty, Health & Intellectual Property Rights with Special Reference to India (Report)

Poverty, Health & Intellectual Property Rights with Special Reference to India (Report)

This paper examines the nexus between poverty and global health with specific focus on IPR protection and attempts to highlight the current global endeavours to overcome barriers to access to medicines for diseases of the poor. The number of very poor people in the world has increased by 10.4 per cent between 1987 and 2001 […]

Local Reference Ranges for Full Blood Count and CD4 Lymphocyte Count Testing (Original Articles) (Cluster of Differentiation) (Report)

Local Reference Ranges for Full Blood Count and CD4 Lymphocyte Count Testing (Original Articles) (Cluster of Differentiation) (Report)

Reference intervals are critically important for the correct interpretation of diagnostic tests. The full blood count and CD4 count are two frequently performed tests in HIV-endemic settings such as Gauteng province, South Africa. Haemoglobin concentration is an independent prognostic indicator in HIV, while CD4 count determines initiation and response to antiretroviral (ARV) treatment. (1) The […]

Ventilator Modes Made Easy: An Easy Reference for RRT's, RN's, and Medical Residents

Ventilator Modes Made Easy: An Easy Reference for RRT’s, RN’s, and Medical Residents

Who says understanding ventilator modes has to be hard?  This book gives you easy to understand information that every RRT, RN, or Resident always wishes they had.  Each mode is described in simple language and answers the three most important questions about ventilator modes: What the mode does, how it works, and when should it […]

Definition of Reference Limits for Autoantibodies to Thyroid Peroxidase and Thyroglobulin in a Large Population of Outpatients Using an Indirect Method Based on Current Data.

Definition of Reference Limits for Autoantibodies to Thyroid Peroxidase and Thyroglobulin in a Large Population of Outpatients Using an Indirect Method Based on Current Data.

Autoantibodies against thyroperoxidase (TPOAb) and thyroglobulin (TgAb) are diagnostic hallmarks and early indicators of autoimmune thyroid diseases (AITD), with an important predictive role in healthy subjects, in pregnant women, and in high-risk patients. (1-4) The estimation of reference limits for thyroid antibodies is still a matter of debate because of the difficulty associated with correctly […]

The Origin of Reference Intervals: A College of American Pathologists Q-Probes Study of "Normal Ranges" Used in 163 Clinical Laboratories (Cap Laboratory Improvement Programs) (Clinical Report)

The Origin of Reference Intervals: A College of American Pathologists Q-Probes Study of “Normal Ranges” Used in 163 Clinical Laboratories (Cap Laboratory Improvement Programs) (Clinical Report)

* Context.–Standards have been developed for establishing reference intervals, but little is known about how intervals are determined in practice, interlaboratory variation in intervals, or errors that occur while setting reference intervals. Objectives.–To determine (1) methods used by clinical laboratories to establish reference intervals for 7 common analytes, (2) variation in intervals, and (3) factors […]