The Relationship Between Gamma-Glutamyl Transferase Levels and Chronic Kidney Disease Among Appalachian Adults (Scientific Article) (Report)

The Relationship Between Gamma-Glutamyl Transferase Levels and Chronic Kidney Disease Among Appalachian Adults (Scientific Article) (Report)

Introduction Serum gamma-glutamyl transferase (GGT), an enzyme responsible for extracellular catabolism of glutathione and a marker of oxidative stress (1) has been shown to be associated with diabetes mellitus (2) and hypertension, (3) which are considered to be independent risk factors for chronic kidney disease (CKD). However, few epidemiological studies have explored the independent relationship […]

The Utility of an Intra-Operative Cystogram with a Simulated Voiding Phase After Endoscopic Treatment of Vesicoureteral Reflux (Scientific Article) (Report)

The Utility of an Intra-Operative Cystogram with a Simulated Voiding Phase After Endoscopic Treatment of Vesicoureteral Reflux (Scientific Article) (Report)

Introduction Vesicoureteral reflux affects one percent of children (1). Traditonally, low grade reflux has been managed with prophylactic antibiotics. Ureteroneocystotomy has been reserved for high grade reflux, children with breakthough urinary tract infections and children with reflux who develop renal scarring. The introduction of subureteral injection bulking agents by Matouschek has altered the management of […]

The Predisposing Factors, Biological Markers, Neuroimaging Techniques and Medical Complications Associated with Alzheimer's Disease (Scientific Article: Special Issue) (Disease/Disorder Overview)

The Predisposing Factors, Biological Markers, Neuroimaging Techniques and Medical Complications Associated with Alzheimer’s Disease (Scientific Article: Special Issue) (Disease/Disorder Overview)

The concept and terminology of dementia is changing. There is a proposal in DSM-V which will be published in the next few years to eliminate the word “dementia” and “mild cognitive disorder” and replace the diagnoses with minor and major neurocognitive disorders. (1) Over time, practitioners have recognized that pure Alzheimer’s dementia is not as […]

Pleuro-Pulmonary Disease in Central South Africa: A Thoracic Surgical Deficiency (Scientific Letters) (Letter to the Editor)

Pleuro-Pulmonary Disease in Central South Africa: A Thoracic Surgical Deficiency (Scientific Letters) (Letter to the Editor)

To the Editor: We wished to estimate the performance gap between thoracic surgical service provision and the burden of thoracic surgical disease in central South Africa (SA). We compared burden of disease data to the number of thoracic operations performed for inflammatory pleuro-pulmonary disease and primary lung cancer. The performance gap was estimated to be […]

Gallstone Pancreatitis in Pediatric Patients--a Common Disease in an Uncommon Population (Scientific Article) (Clinical Report)

Gallstone Pancreatitis in Pediatric Patients–a Common Disease in an Uncommon Population (Scientific Article) (Clinical Report)

Introduction Pediatric pancreatitis remains uncommon in comparison to the adult population. In the United States, 50-60% of adult acute pancreatitis cases in community hospitals are related to cholelithiasis. (1) Pancreatitis in children, however, is most commonly related to trauma, infection, systemic disease, drug reaction, and anatomic abnormalities of the pancreatobiliary tree. (2,3,4) Gallstone pancreatitis is […]

Prevalence of Drug Use in Pregnant West Virginia Patients (Scientific Article: Special Issue) (Report)

Prevalence of Drug Use in Pregnant West Virginia Patients (Scientific Article: Special Issue) (Report)

Introduction Substance abuse in pregnancy is known to have deleterious effects on neonates. These effects differ with respect to the substance ingested and can include neonatal abstinence syndrome (NAS), low birth weight, intrauterine fetal demise, and structural abnormalities such as gastroschisis.