Severe Acute Respiratory Infection with Influenza A (H1N1) During Pregnancy (Scientific Letters) (Report)

Severe Acute Respiratory Infection with Influenza A (H1N1) During Pregnancy (Scientific Letters) (Report)

To the Editor: Pregnant women are at high risk of severe acute respiratory infection if infected with the influenza A (H1N1) virus. On 14 August 2009 the first complicated H1N1 obstetric patient was admitted to the obstetric critical care unit (OCCU) at Tygerberg Hospital with respiratory distress. The clinical picture was that of bronchopneumonia, and […]

Ethical Decision Making in Severe Paediatric Burn Victims (Issues IN MEDICINE)

Ethical Decision Making in Severe Paediatric Burn Victims (Issues IN MEDICINE)

‘The life of a patient is the only life the patient has–can we really make a judgment call on who to treat or not?’ J Puchula (from his address at the 2008 congress of the European Club for Paediatric Burns, Gdansk). The matter of triaging severe burns so that expensive and potentially futile treatment should […]

Pharmacovigilance in Kala-Azar Patients with Severe Thrombocytopenia Caused by Sodium Antimony Gluconate & Miltefosine.

Pharmacovigilance in Kala-Azar Patients with Severe Thrombocytopenia Caused by Sodium Antimony Gluconate & Miltefosine.

Sodium antimony gluconate (SAG) and miltefosine used in the treatment of kala-azar are known to cause several side effects but severe thrombocytopenia has not been reported. Four cases of severe thrombocytopenia, two caused by SAG and two by miltefosine were promptly detected and treated by immediate withdrawal of the offending drugs, platelet and blood transfusions […]

Iodine Deficiency Disorders After a Decade of Universal Salt Iodization in a Severe Iodine Deficiency Region in China (Report)

Iodine Deficiency Disorders After a Decade of Universal Salt Iodization in a Severe Iodine Deficiency Region in China (Report)

Iodine is an essential ingredient for the synthesis of thyroid hormones. Iodine deficiency (ID) causes goiter and different forms of physical and mental retardation. Iodine deficiency disorders (IDD) affect the poor, pregnant woman and preschool children (1,2). Normal levels of thyroid hormones are required for neuronal migration and myelination of the foetal brain, and lack […]

Drotrecogin Alfa (Activated): The First Fda-Approved Treatment for Severe Sepsis (Pharmacology Notes) (Drug Overview)

Drotrecogin Alfa (Activated): The First Fda-Approved Treatment for Severe Sepsis (Pharmacology Notes) (Drug Overview)

Drotrecogin alfa (activated) (Xigris, Eli Lilly and Company, Indianapolis, Ind) is a recombinant form of human activated protein C. It was approved by the Food and Drug Administration in the last quarter of 2001 for the reduction of mortality due to severe sepsis in adult patients who are at high risk of death (1). This […]