Genetic Variations in Androgen Metabolism Genes and Associations with Prostate Cancer in South African Men (Original Articles) (Report)

Genetic Variations in Androgen Metabolism Genes and Associations with Prostate Cancer in South African Men (Original Articles) (Report)

Prostate cancer (PCa) is the second most common histologically diagnosed malignancy in South African men, with an estimated annual incidence rate of 17.8/100 000.1 The age-standardised incidence rate (ASIR) of PCa in South African men in the 55 59-year age range is 56/100 000; this figure rises to 455/100 000 in men older than 75 […]

Association Between Genetic Variations of Apo AI-CIII-AIV Cluster Gene and Hypertriglyceridemic Subjects (Molecular Pathology and Genetics)

Association Between Genetic Variations of Apo AI-CIII-AIV Cluster Gene and Hypertriglyceridemic Subjects (Molecular Pathology and Genetics)

Rather than single gene defect, impaired functions in two or more of the many genes that control lipid transport and metabolism have been suspected to cause inherited lipoprotein disorders or atherosclerosis. The apolipoprotein (apo) AI-CIII-AIV cluster gene is one of such groups. (5) The products of apo AI, CIII, and AIV genes, together with apo […]