The Effect of the Number of Biopsy Cores on the Concordance Between Prostate Biopsy and Prostatectomy Gleason Score: A Prostate Volume-Controlled Study (Clinical Report)

The Effect of the Number of Biopsy Cores on the Concordance Between Prostate Biopsy and Prostatectomy Gleason Score: A Prostate Volume-Controlled Study (Clinical Report)

In 2007, prostate cancer (PCa) was still the most frequent noncutaneous tumor in men, with approximately 218890 new cases expected in the United States. (1) About 50% of US patients with localized disease are treated with radical prostatectomy (RP) (2); however, despite radical surgical treatment, 25% of patients will present with biochemical recurrence and about 10% will die of PCa during a 15-year follow-up period. (3) The Gleason score of RP specimens has been considered one of the most important variables in predicting disease recurrence during the follow-up period. (4) Thus, its definition before surgery would allow a more accurate staging and the choice of an ideal treatment strategy. However, the accuracy of sextant biopsy technique, as standardized by Hodge et al, (5) in predicting RP Gleason score is reported to be only 28% to 45%. (6-8)

The Effect of the Number of Biopsy Cores on the Concordance Between Prostate Biopsy and Prostatectomy Gleason Score: A Prostate Volume-Controlled Study (Clinical Report)

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The Effect of the Number of Biopsy Cores on the Concordance Between Prostate Biopsy and Prostatectomy Gleason Score: A Prostate Volume-Controlled Study (Clinical Report) | | 4.5