The Origin of Reference Intervals: A College of American Pathologists Q-Probes Study of “Normal Ranges” Used in 163 Clinical Laboratories (Cap Laboratory Improvement Programs) (Clinical Report)

The Origin of Reference Intervals: A College of American Pathologists Q-Probes Study of "Normal Ranges" Used in 163 Clinical Laboratories (Cap Laboratory Improvement Programs) (Clinical Report)

* Context.–Standards have been developed for establishing reference intervals, but little is known about how intervals are determined in practice, interlaboratory variation in intervals, or errors that occur while setting reference intervals. Objectives.–To determine (1) methods used by clinical laboratories to establish reference intervals for 7 common analytes, (2) variation in intervals, and (3) factors that contribute to establishment of “outlier” intervals.

The Origin of Reference Intervals: A College of American Pathologists Q-Probes Study of "Normal Ranges" Used in 163 Clinical Laboratories (Cap Laboratory Improvement Programs) (Clinical Report)

The Origin of Reference Intervals: A College of American Pathologists Q-Probes Study of “Normal Ranges” Used in 163 Clinical Laboratories (Cap Laboratory Improvement Programs) (Clinical Report) | | 4.5